Pathogen testing service | cdr labs
CPT CodeDescription
81513Gardnerella vaginalis, Atopobium vaginae, and Lactobacillus species.

Vaginitis Panel

CDR Labs offers a panel of tests to aid in the detection of vaginosis and vaginitis. Our assays detect the three most common causes of infectious vaginitis: bacterial vaginosis, candida vaginitis and trichomoniasis.

Ten million women each year visit their healthcare providers seeking a cure for vaginitis and a third of all women will have symptoms of vaginitis at some point during their lives, most commonly during their reproductive years.1,2 Some types of vaginitis are transferred through sexual activity, while others arise because of an imbalance in the bacterial or fungal makeup of the vaginal microbiome.3 Combined, bacterial vaginosis (BV), candida vaginitis (commonly known as a yeast infection, CV), and trichomoniasis (Trichomonas vaginalis, TV) make up 90% of vaginitis cases.3

The prevalence of bacterial vaginosis or “BV” in the United States is estimated at 21 million among women ages 14–49.6 Healthcare practitioners often overlook the association of untreated BV infections with serious consequences, including pelvic inflammatory disease7, cervicitis8, higher risk of acquiring STIs (chlamydia, gonorrhea, HSV, HIV),9,10,11 spontaneous abortion, and preterm birth12,13.The prevalence of bacterial vaginosis or “BV” in the United States is estimated at 21 million among women ages 14–49.6 Healthcare practitioners often overlook the association of untreated BV infections with serious consequences, including pelvic inflammatory disease7, cervicitis8, higher risk of acquiring STIs (chlamydia, gonorrhea, HSV, HIV),9,10,11 spontaneous abortion, and preterm birth12,13.Our BV assay demonstrates excellent sensitivity and specificity, due to its proprietary algorithm and assay design, targeting Gardnerella vaginalisAtopobium vaginae, and Lactobacillus species. A simple qualitative BV positive or negative result is returned.

References:

  1. Kent HL. Epidemiology of vaginitis. Am J Obstet Gynecol. 1991;165(Part 2): 1168-76.
  2. American College of Obstetricians and Gynecologists. Vaginitis. https://www.acog.org/Patients/FAQs/Vaginitis. Published August 2011. Accessed May 28, 2019.
  3. Paladine HL. Vaginitis: Diagnosis and Treatment. Am Fam Physician. Am Fam Physician. 2018 Mar 1;97(5):321-329.
  4. Koumans EH, Sternberg M, Bruce C, McQuillan G, Kendrick J, Sutton M, Markowitz LE. The prevalence of bacterial vaginosis in the United States, 2001-2004; associations with symptoms, sexual behaviors, and reproductive health. External. Sex Transm Dis. 2007 Nov;34(11):864-9.
  5. Haggerty CL, Hillier SL, Bass DC, Ness RB; PID Evaluation and Clinical Health study investigators. Bacterial vaginosis and anaerobic bacteria are associated with endometritis. Clin Infect Dis. 2004 Oct 1;39(7):990-5. Epub 2004 Sep.
  6. Marrazzo JM, Wiesenfeld HC, Murray PJ, Busse B, Meyn L, Krohn M, Hillier SL. Risk factors for cervicitis among women with bacterial vaginosis. J Infect Dis. 2006 Mar 1;193(5):617-624. Epub 2006 Feb 2.
  7. Bautista CT, Wurapa EK, Sateren WB, Morris SM, Hollingsworth BP, Sanchez JL. Association of Bacterial Vaginosis with Chlamydia and Gonorrhea Among Women in the U.S. Army. Am J Prev Med. 2017;52(5):632-639. DOI: 10.1016/j.amepre.2016.09.016.
  8. Cherpes TL, Meyn LA, Krohn MA, Lurie JG, Hillier SL. Association between acquisition of herpes simplex virus type 2 in women and bacterial vaginosis. Clin Infect Dis. 2003 Aug 1;37(3):319-325.
  9. Cohen CR, Lingappa JR, Baeten JM, et al. Bacterial vaginosis associated with increased risk of female-to-male HIV-1 transmission: a prospective cohort analysis among African couples. PLoS Med. 2012;9(6):e1001251. DOI: 10.1371/journal.pmed.1001251.
  10. Işik G, Demirezen, Dönmez HG, Beksaç MS. Bacterial vaginosis in association with spontaneous abortion and recurrent pregnancy losses. J Cytol. 2016 Jul-Sep;33(3):135-140.
  11. Donders GG, Van Calsteren K, Bellen G, et al. Predictive value for preterm birth of abnormal vaginal flora, bacterial vaginosis and aerobic vaginitis during the first trimester of pregnancy. BJOG. 2009 Sep;116(10):1315-24.